B2Brain vs Reply.io
B2Brain
- Platform: Trade shows and events
- Best For: B2B event lead conversion
- Strength: Offline to online pipeline
- Users: Not specified
Starting at $1,000/show
Reply.io
- Platform: Email, LinkedIn, SMS, WhatsApp, calls
- Best For: Multichannel sales automation
- Strength: AI SDR and personalization
- Users: Not specified
Starting at $49/month
Table of Contents
At a Glance
Lead Capture & Generation
| Feature | B2Brain | Reply.io |
|---|---|---|
| Badge and business card scanning | ✓ Mobile-first scanning with unlimited users on show days | ✗ Not supported; focuses on digital outreach |
| Real-time B2B contact database | ✗ Contextual account intelligence at events | ✓ Access to 1+ billion contacts and 60+ million accounts |
| Voice-to-text note capture | ✓ For faster data entry at busy booths | ✗ AI content generation but no voice notes |
| Contact enrichment | ✓ Enriched leads synced to CRM | ✓ Phone numbers, LinkedIn URLs, and validation |
| AI SDR for automated outreach | ✗ Not available | ✓ Jason AI for sequences and replies |
Sales Engagement & Automation
| Feature | B2Brain | Reply.io |
|---|---|---|
| Multichannel sequences | ✗ Event-focused, not multichannel | ✓ Email, LinkedIn, SMS, WhatsApp, calls |
| Contextual pitch angles and talking points | ✓ Account intelligence for events | ✗ AI variables for personalization |
| LinkedIn automation | ✗ Not supported | ✓ Connection requests, messages, InMails, post engagement |
| Email deliverability tools | ✗ CRM sync only | ✓ Gmail API, warm-up, Postmaster integration |
| Post-event prioritization | ✓ Analytics to focus on valuable prospects | ✗ Unified inbox for ongoing conversations |
Integrations & Collaboration
| Feature | B2Brain | Reply.io |
|---|---|---|
| CRM integrations | ✓ HubSpot, Salesforce, Freshworks | ✓ Multiple CRMs supported via API |
| Slack and Microsoft Teams | ✓ For internal collaboration | ✗ Unified inbox but no specific Slack/Teams |
| SEP integrations | ✓ Salesloft | ✓ Built-in sales engagement |
| Chrome extensions for data | ✗ Browser-based access | ✓ Findy and Name2Email for emails |
| Central dashboard for team monitoring | ✓ Track accounts and team use of intel | ✓ Performance reports and channel efficiency |
Analytics & Reporting
| Feature | B2Brain | Reply.io |
|---|---|---|
| Post-event analytics | ✓ Prioritization of prospects and ROI tracking | ✗ Ongoing campaign analytics |
| AI-generated insights | ✗ Account signals | ✓ AI for sequences and personalization |
| Unified inbox analytics | ✗ Not available | ✓ Manage conversations across channels |
| Team performance tracking | ✓ Monitor intel and lead usage | ✓ Channel efficiency and CSV exports |
Deployment & Accessibility
| Feature | B2Brain | Reply.io |
|---|---|---|
| Mobile-first experience | ✓ For booth scanning and notes | ✗ Web-based with extensions |
| Browser-based access | ✓ No heavy installs | ✓ Full web platform |
| Unlimited users | ✓ On event plans | ✓ From higher tiers |
| Onboarding support | ✓ For platform pricing | ✓ CSM for multichannel |
Pricing Comparison
B2Brain starts at $1,000 per show for event-focused plans, with annual platform access at $5,000/year, while Reply.io offers scalable monthly pricing from $49/month for email outreach up to custom enterprise tiers. B2Brain suits event-heavy teams with CRM integration value, while Reply.io provides flexible scaling for outbound volume.
B2Brain
Trade Show Solution
$1,000/show
Teams attending single events
- Unlimited users at the show
- Unlimited badge, booth, and business card scans on show days
- Pitch angles, talking points, and account signals
- Ability to add and save notes on conversations
- Sync to your CRM with enriched leads
Platform Pricing
$5,000/year
Organizations managing multiple events
- Unlimited users across the organization
- Track and manage accounts throughout the year
- Includes accounts scanned and added at trade shows (with Trade Show packages)
- Integrations to supported CRMs, Slack, and Microsoft Teams
- Onboarding, enablement, and ongoing support
Free Trial
Free
Evaluating core features
- Access to B2Brain via a trial flow from the homepage
- Sample badge to explore the app experience
- Limited-time evaluation of core trade show intelligence features
Reply.io
Sales Outreach – Email Volume 1,000
$49/month
Small teams with low volume
- 1,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
- Email automation with sequences
- ∞ mailboxes supported
Sales Outreach – Email Volume 2,000
$59/month
Growing teams
- 2,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 3,000
$69/month
Mid-volume outreach
- 3,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 5,000
$89/month
Higher volume needs
- 5,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 10,000
$159/month
Scaling teams
- 10,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 25,000
$259/month
Large-scale email
- 25,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 50,000
$459/month
High-volume campaigns
- 50,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Email Volume 100,000
$899/month
Enterprise email volume
- 100,000 active contacts per month
- Unlimited follow-up emails to active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
Sales Outreach – Multichannel
$89/month
Basic multichannel
- Multichannel outreach via email, LinkedIn, SMS, and phone
- 10 mailboxes included
- Unlimited active contacts
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
- Onboarding with CSM team
- Performance and channel efficiency reports
- CSV export of stats
Sales Outreach – Multichannel for Teams
$99/month
Team multichannel
- Multichannel outreach via email, LinkedIn, SMS, and phone
- 5 mailboxes included
- Unlimited email warm-up
- Unlimited emails to active contacts
- 50 live data credits per month
- Anti-spam and deliverability suite
- Support for unlimited users starting from higher contact tiers
- Team performance and channel efficiency reports
- CSV export of stats
Jason AI SDR Starter – 1,000 contacts
$500/month
AI-assisted small scale
- 1,000 active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Jason AI SDR Starter – 2,000 contacts
$800/month
Mid AI scale
- 2,000 active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Jason AI SDR Starter – 3,000 contacts
$1,000/month
Higher AI starter
- 3,000 active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Jason AI SDR Growth – 5,000 contacts
$1,500/month
AI growth stage
- 5,000 active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Jason AI SDR Growth – 10,000 contacts
$3,000/month
Large AI growth
- 10,000 active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Jason AI SDR Enterprise – 25,000+ contacts
Custom
Enterprise AI
- 25,000–50,000+ active contacts per month
- Jason AI SDR agent
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Starter – 1,000 contacts
$800/month
Agency small AI
- 1,000 active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Starter – 2,000 contacts
$1,200/month
Agency mid AI
- 2,000 active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Starter – 3,000 contacts
$1,500/month
Agency higher starter
- 3,000 active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- 1 LinkedIn account included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Growth – 5,000 contacts
$2,500/month
Agency AI growth
- 5,000 active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Growth – 10,000 contacts
$5,000/month
Large agency AI
- 10,000 active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Agency AI SDR Enterprise – 25,000+ contacts
Custom
Enterprise agencies
- 25,000–50,000+ active contacts per month
- Jason AI SDR agent for agencies
- Real-time B2B contacts
- Multiple LinkedIn accounts included
- Unlimited users
- High-accuracy emails
- AI personalization
- Autopilot and copilot modes
- Multichannel automation
- Unlimited mailboxes and warm-ups
Feature Deep Dive
Lead Capture and Enrichment Capabilities
B2Brain
Strengths
- Mobile-first badge, booth, and business card scanning with unlimited scans
- Voice-to-text for quick notes during conversations
- Contextual account intelligence with pitch angles and signals
- Enriched leads automatically synced to CRM
- Unlimited users on event days for large teams
Workflow
Scan badge at booth → Capture voice notes → Add contextual intel → Sync to CRM → Prioritize post-event
Reply.io
Strengths
- Real-time search of 1+ billion B2B contacts
- Chrome extensions for email finding and verification
- Contact enrichment with phones, LinkedIn, and validation
- AI personalization variables for outreach
- High-accuracy data to reduce bounces
Workflow
Search contacts → Enrich data → Validate emails/phones → Build sequences → Automate outreach
B2Brain shines in offline event lead capture with mobile scanning and voice notes, ideal for trade shows. Reply.io excels in digital lead generation with vast databases and enrichment for outbound campaigns. Choose B2Brain for events, Reply.io for scalable digital prospecting.
Sales Engagement and Automation
B2Brain
Strengths
- Talking points and pitch angles based on account intel
- Central dashboard to monitor team lead usage
- Post-event analytics for prospect prioritization
- Integrations with SEPs like Salesloft for follow-up
Limitations
- Limited to event contexts; no multichannel automation
- No AI-generated sequences or replies
Reply.io
Strengths
- Multichannel conditional sequences across 5+ channels
- AI-generated sequences, content, and personalization
- LinkedIn automation for connections and messaging
- Jason AI SDR for autopilot audience selection and replies
- Unified inbox for all conversations
Limitations
- Steep learning curve for complex setups
- No event-specific engagement tools
Reply.io offers comprehensive multichannel automation with AI, perfect for ongoing outbound sales. B2Brain provides targeted event intelligence but lacks broad automation. Reply.io wins for digital sales workflows, B2Brain for event-driven engagement.
Integrations and Analytics
B2Brain
Strengths
- Deep CRM integrations (HubSpot, Salesforce, Freshworks)
- Slack and Teams for collaboration
- Post-event analytics and ROI tracking
- Central dashboard for account and team monitoring
- Browser-based with no installs
Limitations
- Focused on event data; no multichannel reporting
- Limited public documentation
Reply.io
Strengths
- CRM and sales tool integrations
- Performance reports on channel efficiency
- CSV exports and onboarding support
- AI insights for optimization
- Unified inbox analytics
Limitations
- Advanced reporting in higher tiers
- Complexity in setup
B2Brain provides strong event-to-CRM integrations and post-event analytics for ROI proof. Reply.io offers broader multichannel reporting and AI-driven insights. B2Brain is better for event integration, Reply.io for ongoing sales analytics.
Use Case Comparison
B2B Trade Show Team
B2Brain 🏆
Excellent
Designed for booth lead capture, unlimited users, and CRM sync to turn events into pipeline.
Best Plan: Trade Show Solution ($1,000/show)
Score: 10/10
Reply.io
Poor
No event scanning; focused on digital outbound, not offline capture.
Best Plan: Not suitable
Score: 2/10
Outbound SDR Team
B2Brain
Fair
Account intel useful but lacks multichannel automation for daily outbound.
Best Plan: Platform ($5,000/year)
Score: 5/10
Reply.io 🏆
Excellent
AI SDR, multichannel sequences, and data enrichment perfect for high-volume prospecting.
Best Plan: Sales Outreach Multichannel ($89/month)
Score: 10/10
Sales Agency Managing Clients
B2Brain
Good
Unlimited users and integrations help, but no agency-specific workspaces.
Best Plan: Platform ($5,000/year)
Score: 6/10
Reply.io 🏆
Excellent
Agency AI SDR tiers with unlimited users and multichannel for client campaigns.
Best Plan: Agency AI SDR Starter ($800/month)
Score: 9/10
Field Marketing Leader Proving Event ROI
B2Brain 🏆
Excellent
Post-event analytics and prioritization directly address ROI measurement.
Best Plan: Trade Show Solution ($1,000/show)
Score: 10/10
Reply.io
Fair
Campaign analytics available but no event-specific ROI tools.
Best Plan: Sales Outreach ($49+/month)
Score: 4/10
Growth-Stage SaaS Building Pipeline
B2Brain
Good
Event intel integrates with CRM for ABM, but limited to events.
Best Plan: Platform ($5,000/year)
Score: 7/10
Reply.io 🏆
Excellent
Predictable outbound with AI sequences and data for SaaS scaling.
Best Plan: Jason AI SDR Growth ($1,500/month)
Score: 10/10
Sales Org with Large Booth Teams
B2Brain 🏆
Excellent
Unlimited users and mobile scanning remove friction for big teams.
Best Plan: Trade Show Solution ($1,000/show)
Score: 10/10
Reply.io
Poor
Team features but no booth-specific tools.
Best Plan: Not suitable
Score: 3/10
RevOps Team Centralizing Reporting
B2Brain
Good
Dashboard for monitoring, but event-only scope.
Best Plan: Platform ($5,000/year)
Score: 7/10
Reply.io 🏆
Excellent
Centralized multichannel reports and deliverability control.
Best Plan: Sales Outreach Multichannel for Teams ($99/month)
Score: 9/10
Small Team with Occasional Events
B2Brain
Fair
Per-show pricing works but high for infrequent use.
Best Plan: Trade Show Solution ($1,000/show)
Score: 5/10
Reply.io 🏆
Good
Affordable entry for digital leads, scalable as needed.
Best Plan: Sales Outreach 1,000 ($49/month)
Score: 8/10
Revenue Team Running ABM at Events
B2Brain 🏆
Excellent
Contextual intel and CRM sync ideal for account-based event strategies.
Best Plan: Platform ($5,000/year)
Score: 10/10
Reply.io
Good
ABM via personalization but no event focus.
Best Plan: Jason AI SDR Starter ($500/month)
Score: 7/10
High-Volume Outbound Campaigns
B2Brain
Poor
Not designed for volume; event-limited.
Best Plan: Not suitable
Score: 2/10
Reply.io 🏆
Excellent
Scales to 100,000+ contacts with multichannel.
Best Plan: Sales Outreach 100,000 ($899/month)
Score: 10/10
Org Relying on HubSpot/Salesforce
B2Brain 🏆
Excellent
Deep integrations ensure seamless event data flow.
Best Plan: Trade Show Solution ($1,000/show)
Score: 9/10
Reply.io
Good
CRM sync available but broader focus.
Best Plan: Sales Outreach ($49+/month)
Score: 7/10
Budget-Conscious Sales Team
B2Brain
Poor
High per-show cost not ideal for tight budgets.
Best Plan: Not suitable for low budget
Score: 3/10
Reply.io 🏆
Excellent
Starts at $49/month with strong features.
Best Plan: Sales Outreach 1,000 ($49/month)
Score: 9/10
Pros and Cons
B2Brain
Pros
- Highly focused on converting event and trade show activity into qualified pipeline
- Unlimited users on event plans remove friction for large booth teams
- Contextual pitch angles and talking points differentiate it from basic lead scanners
- Strong CRM and collaboration integrations, including HubSpot, Salesforce, Slack, and MS Teams
- Mobile-first and browser-based experience is easy to deploy and adopt
Cons
- Pricing starts at levels that may be high for very small teams or occasional event users
- No detailed self-serve monthly tiers are listed publicly, requiring contact for advanced pricing
- Best value is realized only when integrated with a CRM and structured sales process
- Focused primarily on events and trade shows, not a full marketing automation or sales engagement suite
- Some pages like FAQs and Customers currently resolve to generic or 404-style templates, which may limit publicly available documentation
Reply.io
Pros
- Extensive multichannel sequences across email, LinkedIn, SMS, WhatsApp, and calls
- Built-in B2B data with 1+ billion contacts and advanced filtering
- Strong email deliverability toolkit with Gmail API, warm-up, and Postmaster integration
- Powerful AI SDR (Jason AI) for automated audience selection, sequences, and replies
- Flexible between human-led and AI-led sales workflows
Cons
- Platform complexity and learning curve can be high for new or small teams
- Pricing can become significant at higher contact volumes and AI SDR tiers
- Some advanced features may be overkill for simple or low-volume outreach needs
- Agency and enterprise AI SDR plans require sales conversations for exact pricing
- Not focused on content publishing or social media scheduling compared to specialized tools
Final Verdict
B2Brain and Reply.io target distinct sales challenges: B2Brain bridges offline events to online pipeline with specialized intelligence, while Reply.io powers digital outbound with AI multichannel automation. B2Brain fixes event lead loss, Reply.io scales prospecting efficiency.
Choose B2Brain if events drive your pipeline and you need offline-to-CRM conversion. Opt for Reply.io for digital outbound automation and scaling. Combine them for teams using events to fuel multichannel follow-ups, with B2Brain for capture and Reply.io for engagement.
Overall Scores
B2Brain
Value: 6/10
Reply.io
Value: 8/10
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